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Understanding these primary differences in the pathophysiology between these two disease entities is crucial for clinicians when diagnosing, especially since they share overlapping gastrointestinal symptoms. All studies focused on cannabis exposure (one on medical cannabis), with data spanning 2016–2023 and involving millions of participants across multiple countries. A meta-analysis in Nature Mental Health and related CMAJ data confirmed that high-potency cannabis (over 10–15% THC) and daily use are strongly linked to psychosis.

cannabinoid hyperemesis syndrome

FAQs: Marijuana and Your Health

  • I had no idea how much the weed was hurting my body and mind until I found the gift of Marijuana Anonymous to support my sobriety.
  • Historically, cannabis has been used to stimulate appetite and as an anti-emetic.

Benzodiazepines, with their gamma-aminobutyric acid (GABA) agonistic actions, inhibit the medullary and vestibular nuclei, causing anti-emetic action. Additionally, anxiolytic and sedative properties aid in counteracting the abnormal sympathetic nervous system response, helping in the reduction in vomiting and decreasing pain perception 67. Sympathetic and parasympathetic systems play interlinked roles in emesis. The chemoreceptor trigger zone sends signals via the efferent vagus nerve, triggering responses in the parasympathetic and sympathetic nervous systems.

What is Cannabis Hyperemesis Syndrome?

It’s important to be honest about your marijuana use if you have symptoms of CHS. Without knowing this background, providers often misdiagnose CHS as other conditions, like cyclic vomiting syndrome (CVS). The review included both trials and real-world data, giving a fuller picture than RCTs alone. The biggest limitation is that people who seek out medical cannabis may already be more motivated or have different baselines than those who don’t. Still, the pattern suggests cannabis can meaningfully improve daily life for some patients when other drug addiction options fall short.

Substance Use Disorders and Behavioral Addictions

If you’ve tried everything else and nothing is working, understanding this syndrome might be the key to getting your life back, often with the support of professional marijuana addiction treatment. In patients who do not improve with psychosocial interventions, gabapentin may be used as an adjunctive treatment to aid in addiction recovery. Cannabis withdrawal commonly presents with symptoms such as loss of appetite, anxiety, depression, physical tension, and insomnia, which increases the difficulty in ceasing cannabis use 93. Amitriptyline and lorazepam can be used to mitigate withdrawal effects of cannabis. Furthermore, this process requires considerable effort and motivation from the patient.

However, dropout rates were high in trials because of side effects, and long-term data beyond a year remain limited. Since getting sober, I have not had a single vomiting episode. I have not had a single day where I’ve fought for someone else’s jubilation more than my own. I have not had a single day where I’ve believed the subdued nature cannabis induces is worth sacrificing the joys that everyday life https://ecosoberhouse.com/ can bring you.

  • However, the development of drug candidates for CB1 is challenged by side effects, rapid tolerance buildup, and the risk of abuse 33.
  • A good patient–physician relationship helps achieve CHS remission sooner and avoids unnecessary diagnostic workups 106.
  • This will provide more data on CHS and facilitate the development of targeted novel therapeutic interventions for this condition in the future.
  • Recognizing CHS early-especially in people who frequently use THC products like Canapuff vapes or edibles-can be life-changing.
  • If you notice these issues intensifying alongside your cannabis use, it’s worth investigating further.

The Most Common CHS Symptoms

cannabinoid hyperemesis syndrome

Cannabinoid cannabinoid hyperemesis syndrome Hyperemesis Syndrome (CHS) is a condition that can develop in some individuals who use cannabis regularly. It’s characterized by severe nausea, vomiting, and abdominal pain. Let’s break it down in terms of its stages, causes, symptoms, and what can be done to manage it.